There has been an impending medical crisis since the late 1950's of antibiotic resistant bacterial infections. The plain fact of the matter is that we have a vast body of researchers devoted to comming up with new and different antibiotics, but we are running out of possibilities, and as we do so the new antibiotics are progressively more brutal to the human patients who take them.
With the rise of Vancomycin resistance doctors are simply out of options. So much so that if a Vancomycin resistant strain is identified the standard response is total quarantine. New antibiotics can no longer keep up with newly developing resistances.
There is, however, a theoretical way out. The next generation of antibiotics could be enzymatic anti-toxins, destroying the toxins that the infectious bacteria produce without destroying the bacteria itself. This is not an ideal solution, but it can buy you time to fight the infection with your own immune system, which is largely speaking better than death. The upshot of this meathod is that it does not selectively target nonresistant bacteria- even if a bacteria developed a new toxin it would not be a selective advantage, so resistance would appear slowly, if at all. The downside is that the cost will be higher and the effectiveness lower than any existing treatment.
So there are two strategies open if the next-gens get developed- we can keep using the old antibiotics for as long as they can be at all effective, and continue to give people the best available, for lower prices than the next-gens, but face a total resistance to the older, better drugs sooner.
Or we could ban the use of the older, more effective antibiotics in all but the most lifethreatening cases, allowing them to retain effectiveness for longer, but requiring that the average person pay more for a less effective product for use against common every-day infections.
With the rise of Vancomycin resistance doctors are simply out of options. So much so that if a Vancomycin resistant strain is identified the standard response is total quarantine. New antibiotics can no longer keep up with newly developing resistances.
There is, however, a theoretical way out. The next generation of antibiotics could be enzymatic anti-toxins, destroying the toxins that the infectious bacteria produce without destroying the bacteria itself. This is not an ideal solution, but it can buy you time to fight the infection with your own immune system, which is largely speaking better than death. The upshot of this meathod is that it does not selectively target nonresistant bacteria- even if a bacteria developed a new toxin it would not be a selective advantage, so resistance would appear slowly, if at all. The downside is that the cost will be higher and the effectiveness lower than any existing treatment.
So there are two strategies open if the next-gens get developed- we can keep using the old antibiotics for as long as they can be at all effective, and continue to give people the best available, for lower prices than the next-gens, but face a total resistance to the older, better drugs sooner.
Or we could ban the use of the older, more effective antibiotics in all but the most lifethreatening cases, allowing them to retain effectiveness for longer, but requiring that the average person pay more for a less effective product for use against common every-day infections.
In Soviet ISB, NeS writes YOU!