I only use MSN, so I just stuck with MSN Messenger 7.0 I find it's the easiest to use considering I keep and active journal with it and I like the auto music announcer... the winks and nudges are annoying that's why I just turn them off. I also like the webcam support, I haven't been able to find that for GAIM at all or Trillian, although I'm pretty sure the webcam has support in Trillian.

I only use AIM, so...

AIM + DeadAim. Works perfectly. I've used gaim and trillian but i find them a bit too feature packed. all i really do is IM and put up away messages.

I've been using Gaim so that's what I voted, but I've never tried Trillian and you guys are convincing me so I'm downloading it right now.