Let's ask Purdue:
Apostrophe Use:
http://owl.english.purdue.edu/handouts/grammar/g_apost.html
One may note no mention of either the Grave Accent or the dread Smart Tick.
I can't speak for my typewriter, as I would have to get it out of storage in order to check its layout, but I have never owned a computer with a keyboard including a typographic apostrophe on it.
As such, I have never had the urge to type in the ALT code every time I needed to use an apostrophe. Using a single tick is quite sufficient in almost all cases. Moreover, I've had numerous experiences with the use of typographic apostrophes, particularly Microsoft's so-called Smart Quotes turning into encoding hell, where the apostrophes transform into some other character or often string of characters, when transferring documents between platforms, programs, or even fonts. As such, usually the first thing I do when I run into such a usage is run a Replace to turn them all into ' and " anyways.
Commas after introductions:
http://owl.english.purdue.edu/handouts/grammar/g_commaint.html
General Comma Use:
http://owl.english.purdue.edu/handouts/grammar/g_comma.html
Commas Don't Always Mark Pauses:
http://www.pnc.edu/engl/writingcenter/comdon.html
More Basic Comma Rules:
http://www.pnc.edu/engl/writingcenter/comma.html
Grave Accent Use In English [yes it has some use]:
http://en.wikipedia.org/wiki/Grave_accent#Use_in_English
Now I'm not actually going to go through and quote these all and say who is right or wrong where; however there they are as reputable references [the Purdue ones at least].
This is a very noble view of grammar. Unfortunately, I'm afraid you may be writing in the wrong language for it to hold very true.
Generally when I encounter wonkiness in English grammar, I lay the blame on either the Normans, who basically destroyed English grammar and declensions for all eternity after their conquest, or the Victorians, who had a nasty habit of arbitrarily resurrecting and imposing grammatical rules from Latin in an attempt to 'purify' English.
Russian, however, is not without its grammatical quandaries as well. Unfortunately it's been too long since I spoke it to remember them precisely, but one of them as I recall has to do with inconsistent plural declension of numbers in I think it was the Genitive case. If I recall, there were three groupings of numbers each of which took a different declension, something like: 1, 2-4, 5-20, then 21, 22-24 took the same pattern as 1, 2-4 and so forth.
There is at least one theory about this, though:
http://linguistlist.org/ask-ling/message-details2.cfm?AsklingID=200381728
As to the original quote:
I would be much more inclined to write this as:
"If you are trying to say that the term 'Indie' is applied to bands who are striking it out on their own, I would say that used to be the case; but now the Indie genre is pretty commercialized as well."
In this case, "that India is applied to bands" should not end in a comma as it is an essential clause viz: "If you are trying to say who are striking it out on their own," makes no sense.
Also, I can kill you with my brain.